Effect of titanium-prepared platelet-rich fibrin treatment on the angiogenic biomarkers in gingival crevicular fluid in infrabony defects of patients with chronic periodontitis: A randomized controlled clinical trial.
Identifieur interne : 000090 ( Main/Exploration ); précédent : 000089; suivant : 000091Effect of titanium-prepared platelet-rich fibrin treatment on the angiogenic biomarkers in gingival crevicular fluid in infrabony defects of patients with chronic periodontitis: A randomized controlled clinical trial.
Auteurs : H G Pirebas [Turquie] ; M K Hendek [Turquie] ; U. Kisa [Turquie] ; M. Yalim [Turquie] ; E O Erdemir [Turquie]Source :
- Nigerian journal of clinical practice [ 1119-3077 ] ; 2018.
Descripteurs français
- KwdFr :
- Adulte (MeSH), Adulte d'âge moyen (MeSH), Angiostatines (métabolisme), Bécaplermine (MeSH), Exsudat gingival (métabolisme), Facteur de croissance endothéliale vasculaire de type A (métabolisme), Facteur de croissance fibroblastique de type 2 (métabolisme), Facteurs temps (MeSH), Femelle (MeSH), Fibrine riche en plaquettes (MeSH), Humains (MeSH), Indice parodontal (MeSH), Marqueurs biologiques (métabolisme), Mâle (MeSH), Méthode en double aveugle (MeSH), Néovascularisation physiologique (MeSH), Pancreatic ribonuclease (métabolisme), Parodontite chronique (métabolisme), Parodontite chronique (thérapie), Processus alvéolaire (chirurgie), Protéines proto-oncogènes c-sis (métabolisme), Période postopératoire (MeSH), Titane (MeSH), Transplantation osseuse (MeSH).
- MESH :
- chirurgie : Processus alvéolaire.
- métabolisme : Angiostatines, Exsudat gingival, Facteur de croissance endothéliale vasculaire de type A, Facteur de croissance fibroblastique de type 2, Marqueurs biologiques, Pancreatic ribonuclease, Parodontite chronique, Protéines proto-oncogènes c-sis.
- thérapie : Parodontite chronique.
- Adulte, Adulte d'âge moyen, Bécaplermine, Facteurs temps, Femelle, Fibrine riche en plaquettes, Humains, Indice parodontal, Mâle, Méthode en double aveugle, Néovascularisation physiologique, Période postopératoire, Titane, Transplantation osseuse.
English descriptors
- KwdEn :
- Adult (MeSH), Alveolar Process (surgery), Angiostatins (metabolism), Becaplermin (MeSH), Biomarkers (metabolism), Bone Transplantation (MeSH), Chronic Periodontitis (metabolism), Chronic Periodontitis (therapy), Double-Blind Method (MeSH), Female (MeSH), Fibroblast Growth Factor 2 (metabolism), Gingival Crevicular Fluid (metabolism), Humans (MeSH), Male (MeSH), Middle Aged (MeSH), Neovascularization, Physiologic (MeSH), Periodontal Index (MeSH), Platelet-Rich Fibrin (MeSH), Postoperative Period (MeSH), Proto-Oncogene Proteins c-sis (metabolism), Ribonuclease, Pancreatic (metabolism), Time Factors (MeSH), Titanium (MeSH), Vascular Endothelial Growth Factor A (metabolism).
- MESH :
- chemical , metabolism : Angiostatins, Biomarkers, Fibroblast Growth Factor 2, Proto-Oncogene Proteins c-sis, Ribonuclease, Pancreatic, Vascular Endothelial Growth Factor A.
- metabolism : Chronic Periodontitis, Gingival Crevicular Fluid.
- surgery : Alveolar Process.
- therapy : Chronic Periodontitis.
- Adult, Becaplermin, Bone Transplantation, Double-Blind Method, Female, Humans, Male, Middle Aged, Neovascularization, Physiologic, Periodontal Index, Platelet-Rich Fibrin, Postoperative Period, Time Factors, Titanium.
Abstract
AIM
The aim of this double-blinded, randomized, controlled clinical study was to investigate the effect of titanium-prepared platelet-rich fibrin (T-PRF) treatment on the angiogenic biomarkers in gingival crevicular fluid (GCF) in infrabony defects of patients with chronic periodontitis.
MATERIALS AND METHODS
Twenty five systemically healthy participants who complied with inclusion criteria with periodontal infrabony defects were recruited. In each patient, the infrabony defect of one side of arch was designated as control group (allograft), whereas the infrabony defect on the contralateral side of same arch was designated as test group (allograft + T-PRF). The therapy methods (test or control) were randomly decided. GCF samples were collected at baseline (presurgery) and then the 3rd, 7th, 14th, and 30th days after surgery. Platelet-derived growth factor (PDGF)-BB, vascular endothelial growth factor (VEGF)-A, fibroblast growth factor (FGF)-2, anjiogenin (ANG), angiostatin (ANT) in the GCF samples were measured using human enzyme-linked immunosorbent assay kits.
RESULTS
In both groups, total amounts of PDGF-BB, VEGF-A, FGF-2, ANG, and ANT peaked in the GCF samples obtained at the early postoperative day (day 3) and decreased over time in the samples obtained at the 7th, 14th, and 30th days postsurgery. There were no significant differences between groups for the total amounts of PDGF-BB, VEGF-A, FGF-2, ANG, and ANT at all evaluation periods.
CONCLUSION
Application of T-PRF combined with allograft in infrabony defects of patients with chronic periodontitis had no significant effects on angiogenic biomarkers in GCF.
DOI: 10.4103/1119-3077.224795
PubMed: 29411727
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Kisa</name><affiliation wicri:level="1"><nlm:affiliation>Department of Biochemistry, Faculty of Medicine, Kirikkale University, Kirikkale, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Biochemistry, Faculty of Medicine, Kirikkale University, Kirikkale</wicri:regionArea><wicri:noRegion>Kirikkale</wicri:noRegion></affiliation></author><author><name sortKey="Yalim, M" sort="Yalim, M" uniqKey="Yalim M" first="M" last="Yalim">M. Yalim</name><affiliation wicri:level="1"><nlm:affiliation>Department of Periodontology, Faculty of Dentistry, Gazi University, Ankara, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Periodontology, Faculty of Dentistry, Gazi University, Ankara</wicri:regionArea><wicri:noRegion>Ankara</wicri:noRegion></affiliation></author><author><name sortKey="Erdemir, E O" sort="Erdemir, E O" uniqKey="Erdemir E" first="E O" last="Erdemir">E O Erdemir</name><affiliation wicri:level="1"><nlm:affiliation>Department of Periodontology, Faculty of Dentistry, Kirikkale, Turkey.</nlm:affiliation><country xml:lang="fr">Turquie</country><wicri:regionArea>Department of Periodontology, Faculty of Dentistry, Kirikkale</wicri:regionArea><wicri:noRegion>Kirikkale</wicri:noRegion></affiliation></author></analytic><series><title level="j">Nigerian journal of clinical practice</title><idno type="ISSN">1119-3077</idno><imprint><date when="2018" type="published">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term><term>Alveolar Process (surgery)</term><term>Angiostatins (metabolism)</term><term>Becaplermin (MeSH)</term><term>Biomarkers (metabolism)</term><term>Bone Transplantation (MeSH)</term><term>Chronic Periodontitis (metabolism)</term><term>Chronic Periodontitis (therapy)</term><term>Double-Blind Method (MeSH)</term><term>Female (MeSH)</term><term>Fibroblast Growth Factor 2 (metabolism)</term><term>Gingival Crevicular Fluid (metabolism)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Neovascularization, Physiologic (MeSH)</term><term>Periodontal Index (MeSH)</term><term>Platelet-Rich Fibrin (MeSH)</term><term>Postoperative Period (MeSH)</term><term>Proto-Oncogene Proteins c-sis (metabolism)</term><term>Ribonuclease, Pancreatic (metabolism)</term><term>Time Factors (MeSH)</term><term>Titanium (MeSH)</term><term>Vascular Endothelial Growth Factor A (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term><term>Adulte d'âge moyen (MeSH)</term><term>Angiostatines (métabolisme)</term><term>Bécaplermine (MeSH)</term><term>Exsudat gingival (métabolisme)</term><term>Facteur de croissance endothéliale vasculaire de type A (métabolisme)</term><term>Facteur de croissance fibroblastique de type 2 (métabolisme)</term><term>Facteurs temps (MeSH)</term><term>Femelle (MeSH)</term><term>Fibrine riche en plaquettes (MeSH)</term><term>Humains (MeSH)</term><term>Indice parodontal (MeSH)</term><term>Marqueurs biologiques (métabolisme)</term><term>Mâle (MeSH)</term><term>Méthode en double aveugle (MeSH)</term><term>Néovascularisation physiologique (MeSH)</term><term>Pancreatic ribonuclease (métabolisme)</term><term>Parodontite chronique (métabolisme)</term><term>Parodontite chronique (thérapie)</term><term>Processus alvéolaire (chirurgie)</term><term>Protéines proto-oncogènes c-sis (métabolisme)</term><term>Période postopératoire (MeSH)</term><term>Titane (MeSH)</term><term>Transplantation osseuse (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Angiostatins</term><term>Biomarkers</term><term>Fibroblast Growth Factor 2</term><term>Proto-Oncogene Proteins c-sis</term><term>Ribonuclease, Pancreatic</term><term>Vascular Endothelial Growth Factor A</term></keywords><keywords scheme="MESH" qualifier="chirurgie" xml:lang="fr"><term>Processus alvéolaire</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Chronic Periodontitis</term><term>Gingival Crevicular Fluid</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Angiostatines</term><term>Exsudat gingival</term><term>Facteur de croissance endothéliale vasculaire de type A</term><term>Facteur de croissance fibroblastique de type 2</term><term>Marqueurs biologiques</term><term>Pancreatic ribonuclease</term><term>Parodontite chronique</term><term>Protéines proto-oncogènes c-sis</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Alveolar Process</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Chronic Periodontitis</term></keywords><keywords scheme="MESH" qualifier="thérapie" xml:lang="fr"><term>Parodontite chronique</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Becaplermin</term><term>Bone Transplantation</term><term>Double-Blind Method</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neovascularization, Physiologic</term><term>Periodontal Index</term><term>Platelet-Rich Fibrin</term><term>Postoperative Period</term><term>Time Factors</term><term>Titanium</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Bécaplermine</term><term>Facteurs temps</term><term>Femelle</term><term>Fibrine riche en plaquettes</term><term>Humains</term><term>Indice parodontal</term><term>Mâle</term><term>Méthode en double aveugle</term><term>Néovascularisation physiologique</term><term>Période postopératoire</term><term>Titane</term><term>Transplantation osseuse</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>AIM</b></p><p>The aim of this double-blinded, randomized, controlled clinical study was to investigate the effect of titanium-prepared platelet-rich fibrin (T-PRF) treatment on the angiogenic biomarkers in gingival crevicular fluid (GCF) in infrabony defects of patients with chronic periodontitis.</p></div><div type="abstract" xml:lang="en"><p><b>MATERIALS AND METHODS</b></p><p>Twenty five systemically healthy participants who complied with inclusion criteria with periodontal infrabony defects were recruited. In each patient, the infrabony defect of one side of arch was designated as control group (allograft), whereas the infrabony defect on the contralateral side of same arch was designated as test group (allograft + T-PRF). The therapy methods (test or control) were randomly decided. GCF samples were collected at baseline (presurgery) and then the 3rd, 7th, 14th, and 30th days after surgery. Platelet-derived growth factor (PDGF)-BB, vascular endothelial growth factor (VEGF)-A, fibroblast growth factor (FGF)-2, anjiogenin (ANG), angiostatin (ANT) in the GCF samples were measured using human enzyme-linked immunosorbent assay kits.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>In both groups, total amounts of PDGF-BB, VEGF-A, FGF-2, ANG, and ANT peaked in the GCF samples obtained at the early postoperative day (day 3) and decreased over time in the samples obtained at the 7th, 14th, and 30th days postsurgery. There were no significant differences between groups for the total amounts of PDGF-BB, VEGF-A, FGF-2, ANG, and ANT at all evaluation periods.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>Application of T-PRF combined with allograft in infrabony defects of patients with chronic periodontitis had no significant effects on angiogenic biomarkers in GCF.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">29411727</PMID><DateCompleted><Year>2018</Year><Month>07</Month><Day>18</Day></DateCompleted><DateRevised><Year>2018</Year><Month>12</Month><Day>02</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">1119-3077</ISSN><JournalIssue CitedMedium="Internet"><Volume>21</Volume><Issue>1</Issue><PubDate><Year>2018</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Nigerian journal of clinical practice</Title><ISOAbbreviation>Niger J Clin Pract</ISOAbbreviation></Journal><ArticleTitle>Effect of titanium-prepared platelet-rich fibrin treatment on the angiogenic biomarkers in gingival crevicular fluid in infrabony defects of patients with chronic periodontitis: A randomized controlled clinical trial.</ArticleTitle><Pagination><MedlinePgn>69-75</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.4103/1119-3077.224795</ELocationID><Abstract><AbstractText Label="AIM" NlmCategory="OBJECTIVE">The aim of this double-blinded, randomized, controlled clinical study was to investigate the effect of titanium-prepared platelet-rich fibrin (T-PRF) treatment on the angiogenic biomarkers in gingival crevicular fluid (GCF) in infrabony defects of patients with chronic periodontitis.</AbstractText><AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">Twenty five systemically healthy participants who complied with inclusion criteria with periodontal infrabony defects were recruited. In each patient, the infrabony defect of one side of arch was designated as control group (allograft), whereas the infrabony defect on the contralateral side of same arch was designated as test group (allograft + T-PRF). The therapy methods (test or control) were randomly decided. GCF samples were collected at baseline (presurgery) and then the 3rd, 7th, 14th, and 30th days after surgery. Platelet-derived growth factor (PDGF)-BB, vascular endothelial growth factor (VEGF)-A, fibroblast growth factor (FGF)-2, anjiogenin (ANG), angiostatin (ANT) in the GCF samples were measured using human enzyme-linked immunosorbent assay kits.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">In both groups, total amounts of PDGF-BB, VEGF-A, FGF-2, ANG, and ANT peaked in the GCF samples obtained at the early postoperative day (day 3) and decreased over time in the samples obtained at the 7th, 14th, and 30th days postsurgery. There were no significant differences between groups for the total amounts of PDGF-BB, VEGF-A, FGF-2, ANG, and ANT at all evaluation periods.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Application of T-PRF combined with allograft in infrabony defects of patients with chronic periodontitis had no significant effects on angiogenic biomarkers in GCF.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Pirebas</LastName><ForeName>H G</ForeName><Initials>HG</Initials><AffiliationInfo><Affiliation>Private Dentist, Istanbul, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hendek</LastName><ForeName>M K</ForeName><Initials>MK</Initials><AffiliationInfo><Affiliation>Department of Periodontology, Faculty of Dentistry, Kirikkale, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kisa</LastName><ForeName>U</ForeName><Initials>U</Initials><AffiliationInfo><Affiliation>Department of Biochemistry, Faculty of Medicine, Kirikkale University, Kirikkale, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yalim</LastName><ForeName>M</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Periodontology, Faculty of Dentistry, Gazi University, Ankara, Turkey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Erdemir</LastName><ForeName>E O</ForeName><Initials>EO</Initials><AffiliationInfo><Affiliation>Department of Periodontology, Faculty of Dentistry, Kirikkale, Turkey.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016449">Randomized Controlled Trial</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>India</Country><MedlineTA>Niger J Clin Pract</MedlineTA><NlmUniqueID>101150032</NlmUniqueID></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D015415">Biomarkers</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D020574">Proto-Oncogene Proteins c-sis</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D042461">Vascular Endothelial Growth Factor A</NameOfSubstance></Chemical><Chemical><RegistryNumber>103107-01-3</RegistryNumber><NameOfSubstance UI="D016222">Fibroblast Growth Factor 2</NameOfSubstance></Chemical><Chemical><RegistryNumber>1B56C968OA</RegistryNumber><NameOfSubstance UI="D000077214">Becaplermin</NameOfSubstance></Chemical><Chemical><RegistryNumber>86090-08-6</RegistryNumber><NameOfSubstance UI="D043168">Angiostatins</NameOfSubstance></Chemical><Chemical><RegistryNumber>D1JT611TNE</RegistryNumber><NameOfSubstance UI="D014025">Titanium</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.1.27.-</RegistryNumber><NameOfSubstance UI="C046366">angiogenin</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.1.27.5</RegistryNumber><NameOfSubstance UI="D012259">Ribonuclease, Pancreatic</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000539" MajorTopicYN="N">Alveolar Process</DescriptorName><QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D043168" MajorTopicYN="N">Angiostatins</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000077214" MajorTopicYN="N">Becaplermin</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015415" MajorTopicYN="N">Biomarkers</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016025" MajorTopicYN="N">Bone Transplantation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055113" MajorTopicYN="N">Chronic Periodontitis</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004311" MajorTopicYN="N">Double-Blind Method</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016222" MajorTopicYN="N">Fibroblast Growth Factor 2</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005883" MajorTopicYN="N">Gingival Crevicular Fluid</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018919" MajorTopicYN="N">Neovascularization, Physiologic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010512" MajorTopicYN="N">Periodontal Index</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000073183" MajorTopicYN="Y">Platelet-Rich Fibrin</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011184" MajorTopicYN="N">Postoperative Period</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020574" MajorTopicYN="N">Proto-Oncogene Proteins c-sis</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012259" MajorTopicYN="N">Ribonuclease, Pancreatic</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014025" MajorTopicYN="N">Titanium</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D042461" MajorTopicYN="N">Vascular Endothelial Growth Factor A</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2018</Year><Month>2</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2018</Year><Month>2</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2018</Year><Month>7</Month><Day>19</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">29411727</ArticleId><ArticleId IdType="pii">NigerJClinPract_2018_21_1_69_224795</ArticleId><ArticleId IdType="doi">10.4103/1119-3077.224795</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Turquie</li></country></list><tree><country name="Turquie"><noRegion><name sortKey="Pirebas, H G" sort="Pirebas, H G" uniqKey="Pirebas H" first="H G" last="Pirebas">H G Pirebas</name></noRegion><name sortKey="Erdemir, E O" sort="Erdemir, E O" uniqKey="Erdemir E" first="E O" last="Erdemir">E O Erdemir</name><name sortKey="Hendek, M K" sort="Hendek, M K" uniqKey="Hendek M" first="M K" last="Hendek">M K Hendek</name><name sortKey="Kisa, U" sort="Kisa, U" uniqKey="Kisa U" first="U" last="Kisa">U. 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